2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N12093
    Cevadine
    		Inhibitor 98.76%
    Cevadine is a voltage-sensitive sodium channel agonist. Cevadine has insecticidal activity.
    Cevadine
  • HY-B1455S1
    Clindamycin-13C,d3
    		Inhibitor ≥99.0%
    Clindamycin-13C,d3 is the 13C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria.
    Clindamycin-<sup>13</sup>C,d<sub>3</sub>
  • HY-E70250
    Neocryptolepine
    		Inhibitor 98.05%
    Neocryptolepine (Cryptotackieine) has antiplasmodial activity. Neocryptolepine also shows antibacterial activity against Gram-positive bacteria (MIC < 100 μg/mL), and antifungal activity.
    Neocryptolepine
  • HY-18716
    Dextrorotation nimorazole phosphate ester
    		Inhibitor ≥98.0%
    Dextrorotation nimorazole phosphate ester is an anti-anaerobic and anti-parasitic agent.
    Dextrorotation nimorazole phosphate ester
  • HY-N0978
    1,2,3,19-Tetrahydroxy-12-ursen-28-oic acid
    		Inhibitor ≥98.0%
    1,2,3,19-Tetrahydroxy-12-ursen-28-oic acid is a Triterpenoid that isolated from the plant of Agrimonia Pilosa with antimalarial and antidiabetic activities.
    1,2,3,19-Tetrahydroxy-12-ursen-28-oic acid
  • HY-22044
    ICA
    		Inhibitor 99.92%
    ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 µM.
    ICA
  • HY-123905A
    LIN28 inhibitor LI71 enantiomer
    		Inhibitor 99.68%
    LIN28 inhibitor LI71 enantiomer is the less active enantiomer of LIN28 inhibitor LI71 (HY-123905). LIN28 inhibitor LI71 is a LIN28 inhibitor that effectively inhibits LIN28:let-7 binding (IC50: 7 μM). LIN28 inhibitor LI71 can abolish LIN28-mediated oligouridylation of let-7 precursor (IC50: 27 μM). LIN28 inhibitor LI71 has potential application value in LIN28-driven cancer research. LIN28 inhibitor LI71 inhibits the interaction of cold shock protein of Plasmodium falciparum (PfCoSP) with DNA and α/β tubulin and has an inhibitory effect on Plasmodium falciparum.
    LIN28 inhibitor LI71 enantiomer
  • HY-148433
    SpdSyn binder-1
    SpdSyn binder-1 is a weak binder, which binds in the active site of plasmodium falciparum spermidine synthase. SpdSyn binder-1 can be used for the research of malaria.
    SpdSyn binder-1
  • HY-B0806AS1
    Proguanil-d6 hydrochloride
    		Inhibitor 98.73%
    Proguanil-d6 hydrochloride is the deuterium labeled Proguanil hydrochloride (HY-B0806A). Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.
    Proguanil-d6 hydrochloride
  • HY-N7489
    β-Hederin
    		Inhibitor
    β-Hederin, a saponin isolated from Hedera helix L.(Araliaceae), possesses antileishmanial activity. β-Hederin exhibits IC50 values of 1.5 μM, 68 nM and 4.57 μM in L. Mexicana promastigotes, L. mexicana amastigotes and THP1 cells, respectively.
    β-Hederin
  • HY-B1313
    Lobendazole
    		Inhibitor 99.49%
    Lobendazole is a potent anthelmintic. Lobendazole inhibits Giardia intestinalis strains.
    Lobendazole
  • HY-12785S
    Albendazole sulfoxide-d3
    		Inhibitor 99.79%
    Albendazole sulfoxide-d3 is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.
    Albendazole sulfoxide-d<sub>3</sub>
  • HY-W049875
    Nitroxynil
    		Inhibitor 98.71%
    Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica.
    Nitroxynil
  • HY-N9320
    13,21-Dihydroeurycomanone
    		Inhibitor 98.11%
    13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii.
    13,21-Dihydroeurycomanone
  • HY-B1056
    Procodazole
    		Inhibitor 99.73%
    Procodazole is an orally active enhancer and a non-specific active immune protector against viral and bacterial infections. Procodazole also exhibits antiparasitic activity. In addition, Procodazole is a carbonic anhydrase inhibitor with antitumor activity.
    Procodazole
  • HY-U00295
    Melarsonyl
    		Inhibitor
    Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.
    Melarsonyl
  • HY-153021
    NMT-IN-1
    		Inhibitor ≥98.0%
    NMT-IN-1 (compound 9) is a potent N-Myristoyltransferase (NMT) Inhibitor with IC50 values of 31 and 66 μM for TbNMT and hNMT, respectively. NMT-IN-1 can be used in research of african trypanosomiasis.
    NMT-IN-1
  • HY-18719ES
    Endoxifen-d5
    		Inhibitor
    Endoxifen-d5 is the deuterium labeled Endoxifen. Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study.
    Endoxifen-d<sub>5</sub>
  • HY-135648
    PfDHODH-IN-1
    		Inhibitor 99.12%
    PfDHODH-IN-1 is an analogue of the active metabolite of Leflunomide. PfDHODH-IN-1 is a Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor. PfDHODH-IN-1 has antimalarial activity.
    PfDHODH-IN-1
  • HY-N0924A
    (±)-Stylopine hydrochloride
    		99.66%
    (±)-Stylopine (Tetrahydrocoptisine) hydrochloride is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities.
    (±)-Stylopine hydrochloride
Parasite Isoform Comparison

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